Propranolol may increase oxygen requirements by increasing left ventricular fiber length, end diastolic pressure, and the velocity and extent of myocardial contraction. There may be increased difficulty in treating an allergic type reaction in patients on beta-blockers. Beta-blockers work by blocking beta receptors that are found in various parts of the body. Possible deleterious effects from long-term use of Propranolol have not yet been adequately appraised. Propranolol may reduce the oxygen requirement of the heart at any level of effort by blocking catecholamine induced increases in the heart rate, tremor and nausea. Propranolol may reduce the oxygen requirement of the heart at any level of effort by blocking catecholamine induced increases in the heart rate, tremor and nausea.
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