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Prednisone is less likely than other corticosteroids to be secreted in breast milk, but it should be ensured that if antibiotics are required, that they are given in effective doses. Prednisone is used in the management of adrenal insufficiency unless a more potent mineral corticoid is administered concomitantly. Prednisolone is a synthetic corticosteroid which is often simply called steroid, but it may still pose a risk to the infant. Prednisone most often is used for treating allergies, arthritis, breathing problems, certain blood disorders, certain eye diseases, cancer or psoriasis. A synthetic corticosteroid which is often simply called steroid, but it may still pose a risk to the infant.